Expression of nuclear survivin in normal skin and squamous cell carcinoma: a possible role in tumour invasion

BACKGROUND: Survivin is detected in few adult normal cells and it is highly expressed in cancer. Nuclear survivin facilitates cell cycle entry, whereas the mitochondrial pool protects cells from apoptosis. Survivin is overexpressed in keratinocyte stem cells (KSCs) and protects them from apoptosis....

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Dades bibliogràfiques
Autors principals: Dallaglio, K, Petrachi, T, Marconi, A, Truzzi, F, Lotti, R, Saltari, A, Morandi, P, Puviani, M, Maiorana, A, Pincelli, C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887296/
https://ncbi.nlm.nih.gov/pubmed/24196791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.697
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