Expression of nuclear survivin in normal skin and squamous cell carcinoma: a possible role in tumour invasion

BACKGROUND: Survivin is detected in few adult normal cells and it is highly expressed in cancer. Nuclear survivin facilitates cell cycle entry, whereas the mitochondrial pool protects cells from apoptosis. Survivin is overexpressed in keratinocyte stem cells (KSCs) and protects them from apoptosis....

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Detalhes bibliográficos
Main Authors: Dallaglio, K, Petrachi, T, Marconi, A, Truzzi, F, Lotti, R, Saltari, A, Morandi, P, Puviani, M, Maiorana, A, Pincelli, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887296/
https://ncbi.nlm.nih.gov/pubmed/24196791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.697
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