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Probing protein interactions in living mammalian cells on a microtubule bench

Microtubules are μm-long cylinders of about 25 nm in diameter which are present in the cytoplasm of eukaryotic cells. Here, we have developed a new method which uses these cylindrical structures as platforms to detect protein interactions in cells. The principle is simple: a protein of interest used...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Boca, Mirela, Kretov, Dmitry A., Desforges, Bénédicte, Mephon-Gaspard, Alix, Curmi, Patrick A., Pastré, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661529/
https://ncbi.nlm.nih.gov/pubmed/26610591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17304
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