Pharmacokinetics and Dosimetry Studies for Optimization of Pretargeted Radioimmunotherapy in CEA-Expressing Advanced Lung Cancer Patients

OBJECTIVES: A phase I pretargeted radioimmunotherapy trial (EudractCT 200800603096) was designed in patients with metastatic lung cancer expressing carcinoembryonic antigen (CEA) to optimize bispecific antibody and labeled peptide doses, as well as the delay between their injections. METHODS: Three...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Bodet-Milin, Caroline, Ferrer, Ludovic, Rauscher, Aurore, Masson, Damien, Rbah-Vidal, Latifa, Faivre-Chauvet, Alain, Cerato, Evelyne, Rousseau, Caroline, Hureaux, José, Couturier, Olivier, Salaün, Pierre-Yves, Goldenberg, David M., Sharkey, Robert M., Kraeber-Bodéré, Françoise, Barbet, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661432/
https://ncbi.nlm.nih.gov/pubmed/26640780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2015.00084
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