The β5-Loop and Lid Domain Contribute to the Substrate Specificity of Pancreatic Lipase-related Protein 2 (PNLIPRP2)

Pancreatic triglyceride lipase (PNLIP) is essential for dietary fat digestion in children and adults, whereas a homolog, pancreatic lipase-related protein 2 (PNLIPRP2), is critical in newborns. The two lipases are structurally similar, yet they have different substrate specificities. PNLIP only clea...

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Vydáno v:J Biol Chem
Hlavní autoři: Xiao, Xunjun, Lowe, Mark E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Lipids
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661400/
https://ncbi.nlm.nih.gov/pubmed/26494624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.683375
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