Pancreatic Lipase-related Protein-2 (PLRP2) Can Contribute to Dietary Fat Digestion in Human Newborns

In newborn mice, PLRP2 is essential for fat digestion. In human infants, the role of PLRP2 in fat digestion is unclear, as it has poor activity against long-chain triglycerides in vitro. Also, many infants carry a genetic polymorphism resulting in a truncated protein, PLRP2 W340X, which may impact f...

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Bibliographic Details
Main Authors: Xiao, Xunjun, Mukherjee, Amitava, Ross, Leah E., Lowe, Mark E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Lipids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143598/
https://ncbi.nlm.nih.gov/pubmed/21652702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.249813
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