Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination

Histone H3 lysine 4 (H3K4) methylation is a dynamic modification. In budding yeast, H3K4 methylation is catalyzed by the Set1-COMPASS methyltransferase complex and is removed by Jhd2, a JMJC domain family demethylase. The catalytic JmjC and JmjN domains of Jhd2 have the ability to remove all three d...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Huang, Fu, Ramakrishnan, Saravanan, Pokhrel, Srijana, Pflueger, Christian, Parnell, Timothy J., Kasten, Margaret M., Currie, Simon L., Bhachech, Niraja, Horikoshi, Masami, Graves, Barbara J., Cairns, Bradley R., Bhaskara, Srividya, Chandrasekharan, Mahesh B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661393/
https://ncbi.nlm.nih.gov/pubmed/26451043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693085
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