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Regulation of Synapse Structure and Function by the Drosophila Tumor Suppressor Gene dlg

Mutations of the tumor suppressor gene discs-large (dlg) lead to postsynaptic structural defects. Here, we report that mutations in dlg also result in larger synaptic currents at fly neuromuscular junctions. By selectively targeting DLG protein to either muscles or motorneurons using Gal-4 enhancer...

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Detalles Bibliográficos
Publicado en:Neuron
Main Authors: Budnik, Vivian, Koh, Young-Ho, Guan, Bo, Hartmann, Beate, Hough, Colleen, Woods, Daniel, Gorczyca, Michael
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661176/
https://ncbi.nlm.nih.gov/pubmed/8893021
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