Regulation of Synapse Structure and Function by the Drosophila Tumor Suppressor Gene dlg

Mutations of the tumor suppressor gene discs-large (dlg) lead to postsynaptic structural defects. Here, we report that mutations in dlg also result in larger synaptic currents at fly neuromuscular junctions. By selectively targeting DLG protein to either muscles or motorneurons using Gal-4 enhancer...

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Bibliographic Details
Published in:Neuron
Main Authors: Budnik, Vivian, Koh, Young-Ho, Guan, Bo, Hartmann, Beate, Hough, Colleen, Woods, Daniel, Gorczyca, Michael
Format: Artigo
Language:Inglês
Published: 1996
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661176/
https://ncbi.nlm.nih.gov/pubmed/8893021
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