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POD-1/Tcf21 overexpression reduces endogenous SF-1 and StAR expression in rat adrenal cells
During gonad and adrenal development, the POD-1/capsulin/TCF21transcription factor negatively regulates SF-1/NR5A1expression, with higher SF-1 levels being associated with increased adrenal cell proliferation and tumorigenesis. In adrenocortical tumor cells, POD-1 binds to the SF-1 E-box promoter re...
Shranjeno v:
| izdano v: | Braz J Med Biol Res |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Associação Brasileira de Divulgação Científica
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4661024/ https://ncbi.nlm.nih.gov/pubmed/26421867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20154748 |
| Oznake: |
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