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Helix-Capping Histidines: Diversity of N–H···N Hydrogen Bond Strength Revealed by (2h)J(NN) Scalar Couplings

[Image: see text] In addition to its well-known roles as an electrophile and general acid, the side chain of histidine often serves as a hydrogen bond (H-bond) acceptor. These H-bonds provide a convenient pH-dependent switch for local structure and functional motifs. In hundreds of instances, a hist...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Preimesberger, Matthew R., Majumdar, Ananya, Rice, Selena L., Que, Lauren, Lecomte, Juliette T. J.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2015
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660981/
https://ncbi.nlm.nih.gov/pubmed/26523621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01002
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