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Introduction of a covalent histidine–heme linkage in a hemoglobin: A promising tool for heme protein engineering
The hemoglobins of the cyanobacteria Synechococcus and Synechocystis (GlbNs) are capable of spontaneous and irreversible attachment of the b heme to the protein matrix. The reaction, which saturates the heme 2-vinyl by addition of a histidine residue, is reproduced in vitro by preparing the recombin...
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| Pubblicato in: | J Inorg Biochem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4278642/ https://ncbi.nlm.nih.gov/pubmed/25304367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2014.09.009 |
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