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Introduction of a covalent histidine–heme linkage in a hemoglobin: A promising tool for heme protein engineering

The hemoglobins of the cyanobacteria Synechococcus and Synechocystis (GlbNs) are capable of spontaneous and irreversible attachment of the b heme to the protein matrix. The reaction, which saturates the heme 2-vinyl by addition of a histidine residue, is reproduced in vitro by preparing the recombin...

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Bibliografski detalji
Izdano u:J Inorg Biochem
Glavni autori: Rice, Selena L., Preimesberger, Matthew R., Johnson, Eric A., Lecomte, Juliette T. J., Jenkins, T. C.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278642/
https://ncbi.nlm.nih.gov/pubmed/25304367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2014.09.009
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