Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein

INTRODUCTION: Parkinson’s disease (PD) and multiple system atrophy (MSA) are neurodegenerative diseases that are characterized by the intracellular accumulation of alpha-synuclein containing aggregates. Recent increasing evidence suggests that Parkinson’s disease and MSA pathology spread throughout...

Full description

Saved in:
Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Bernis, Maria E., Babila, Julius T., Breid, Sara, Wüsten, Katharina Annick, Wüllner, Ullrich, Tamgüney, Gültekin
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660655/
https://ncbi.nlm.nih.gov/pubmed/26612754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0254-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items