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Fitting Proportional Odds Model to Case-Control data with Incorporating Hardy-Weinberg Equilibrium

Genetic association studies have been proved to be an efficient tool to reveal the aetiology of many human complex diseases and traits. When the phenotype is binary, the logistic regression model is commonly employed to evaluate the association strength of the genetic variants predispose to human di...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Wei, Zhang, Zehui, Li, Xinmin, Li, Qizhai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660314/
https://ncbi.nlm.nih.gov/pubmed/26607176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17286
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