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Fitting Proportional Odds Model to Case-Control data with Incorporating Hardy-Weinberg Equilibrium

Genetic association studies have been proved to be an efficient tool to reveal the aetiology of many human complex diseases and traits. When the phenotype is binary, the logistic regression model is commonly employed to evaluate the association strength of the genetic variants predispose to human di...

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Опубликовано в: :Sci Rep
Главные авторы: Zhang, Wei, Zhang, Zehui, Li, Xinmin, Li, Qizhai
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660314/
https://ncbi.nlm.nih.gov/pubmed/26607176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17286
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