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Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue

The developing dorsomedial telencephalon includes the medial pallium, which goes on to form the hippocampus. Generating a reliable source of human hippocampal tissue is an important step for cell-based research into hippocampus-related diseases. Here we show the generation of functional hippocampal...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Sakaguchi, Hideya, Kadoshima, Taisuke, Soen, Mika, Narii, Nobuhiro, Ishida, Yoshihito, Ohgushi, Masatoshi, Takahashi, Jun, Eiraku, Mototsugu, Sasai, Yoshiki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660208/
https://ncbi.nlm.nih.gov/pubmed/26573335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9896
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