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A RHO Small GTPase Regulator ABR Secures Mitotic Fidelity in Human Embryonic Stem Cells

Pluripotent stem cells can undergo repeated self-renewal while retaining genetic integrity, but they occasionally acquire aneuploidy during long-term culture, which is a practical obstacle for medical applications of human pluripotent stem cells. In this study, we explored the biological roles of AB...

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Библиографические подробности
Опубликовано в: :Stem Cell Reports
Главные авторы: Ohgushi, Masatoshi, Minaguchi, Maki, Eiraku, Mototsugu, Sasai, Yoshiki
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511046/
https://ncbi.nlm.nih.gov/pubmed/28579391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.05.003
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