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Recent contributions of Structure-Based Drug Design to the development of antibacterial compounds

According to a Pew Research study published in February 2015, there are 37 antibacterial programs currently in clinical trials in the United States. Protein structure-based methods for guiding small molecule design were used in at least 34 of these programs. Typically, this occurred at an early stag...

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Bibliografiske detaljer
Udgivet i:Curr Opin Microbiol
Main Authors: Staker, Bart L., Buchko, Garry W., Myler, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659754/
https://ncbi.nlm.nih.gov/pubmed/26458180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2015.09.003
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