Characterisation of the Candida albicans Phosphopantetheinyl Transferase Ppt2 as a Potential Antifungal Drug Target

Antifungal drugs acting via new mechanisms of action are urgently needed to combat the increasing numbers of severe fungal infections caused by pathogens such as Candida albicans. The phosphopantetheinyl transferase of Aspergillus fumigatus, encoded by the essential gene pptB, has previously been id...

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Udgivet i:PLoS One
Main Authors: Dobb, Katharine S., Kaye, Sarah J., Beckmann, Nicola, Thain, John L., Stateva, Lubomira, Birch, Mike, Oliver, Jason D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659657/
https://ncbi.nlm.nih.gov/pubmed/26606674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143770
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