Characterisation of the Candida albicans Phosphopantetheinyl Transferase Ppt2 as a Potential Antifungal Drug Target

Antifungal drugs acting via new mechanisms of action are urgently needed to combat the increasing numbers of severe fungal infections caused by pathogens such as Candida albicans. The phosphopantetheinyl transferase of Aspergillus fumigatus, encoded by the essential gene pptB, has previously been id...

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Veröffentlicht in:PLoS One
Hauptverfasser: Dobb, Katharine S., Kaye, Sarah J., Beckmann, Nicola, Thain, John L., Stateva, Lubomira, Birch, Mike, Oliver, Jason D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659657/
https://ncbi.nlm.nih.gov/pubmed/26606674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143770
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