Broadly neutralizing alphavirus antibodies bind an epitope on E2 and inhibit entry and egress

We screened a panel of mouse and human monoclonal antibodies (MAbs) against chikungunya virus and identified several with inhibitory activity against multiple alphaviruses. Passive transfer of broadly neutralizing MAbs protected mice against infection by chikungunya, Mayaro, and O’nyong’nyong alphav...

詳細記述

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書誌詳細
出版年:Cell
主要な著者: Fox, Julie M., Long, Feng, Edeling, Melissa A., Lin, Hueylie, van Duijl-Richter, Mareike K.S., Fong, Rachel H., Kahle, Kristen M., Smit, Jolanda M., Jin, Jing, Simmons, Graham, Doranz, Benjamin J., Crowe, James E., Fremont, Daved H., Rossmann, Michael G., Diamond, Michael S.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659373/
https://ncbi.nlm.nih.gov/pubmed/26553503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.10.050
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