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Serum levels of sclerostin, Dickkopf-1, and secreted frizzled-related protein-4 are not changed in individuals with high bone mass causing mutations in LRP5

SUMMARY: We compared circulating levels of Wnt inhibitors among patients with high bone mass mutations in LRP5, unaffected kindred, and unrelated normal controls. Inhibitors were unchanged in affected and unaffected kindred. We saw no meaningful differences between controls and affected individuals....

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Detalhes bibliográficos
Publicado no:Osteoporos Int
Main Authors: Simpson, C. A., Foer, D., Lee, G. S., Bihuniak, J., Sun, B., Sullivan, R., Belsky, J., Insogna, K. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659359/
https://ncbi.nlm.nih.gov/pubmed/24927689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00198-014-2767-5
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