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Bone Matrix Levels of Dickkopf and Sclerostin are Positively Correlated with Bone Mass and Strength in Postmenopausal Osteoporosis

Wnt signaling plays a pivotal role in maintaining bone mass. Secreted pathway modulators such as sclerostin (SOST) and Dickkopfs (DKKs) may influence bone mass inhibiting the canonical Wnt pathway. We evaluated whether bone protein content of secreted Wnt antagonists is related to age, bone mass, an...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ueland, Thor, Stilgren, Lis, Bollerslev, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627473/
https://ncbi.nlm.nih.gov/pubmed/31197079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20122896
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