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Granulocyte colony-stimulating factor exacerbates hematopoietic stem cell injury after irradiation
BACKGROUND: Exposure to a moderate to high dose of ionizing radiation (IR) not only causes acute radiation syndrome but also induces long-term (LT) bone marrow (BM) injury. The latter effect of IR is primarily attributed to the induction of hematopoietic stem cell (HSC) senescence. Granulocyte colon...
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| Veröffentlicht in: | Cell Biosci |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4659162/ https://ncbi.nlm.nih.gov/pubmed/26609358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0057-3 |
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