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Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice

Exposure to ionizing radiation (IR) increases the production of reactive oxygen species (ROS) not only by the radiolysis of water but also through IR-induced perturbation of the cellular metabolism and disturbance of the balance of reduction/oxidation reactions. Our recent studies showed that the in...

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Publicat a:Free Radic Biol Med
Autors principals: Xu, Guoshun, Wu, Hongying, Zhang, Junling, Li, Deguan, Wang, Yueying, Wang, Yingying, Zhang, Heng, Lu, Lu, Li, Chengcheng, Huang, Song, Xing, Yonghua, Zhou, Daohong, Meng, Aimin
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707049/
https://ncbi.nlm.nih.gov/pubmed/26086617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.05.045
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