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Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice

Exposure to ionizing radiation (IR) increases the production of reactive oxygen species (ROS) not only by the radiolysis of water but also through IR-induced perturbation of the cellular metabolism and disturbance of the balance of reduction/oxidation reactions. Our recent studies showed that the in...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Xu, Guoshun, Wu, Hongying, Zhang, Junling, Li, Deguan, Wang, Yueying, Wang, Yingying, Zhang, Heng, Lu, Lu, Li, Chengcheng, Huang, Song, Xing, Yonghua, Zhou, Daohong, Meng, Aimin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707049/
https://ncbi.nlm.nih.gov/pubmed/26086617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.05.045
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