In vitro activity of phospholipase A(2) and of peptides from Crotalus durissus terrificus venom against amastigote and promastigote forms of Leishmania (L.) infantum chagasi

BACKGROUND: American visceral leishmaniasis is caused by the intracellular parasite Leishmania (L.) infantum chagasi, and transmitted by the sand fly Lutzomyia longipalpis. Since treatment is based on classical chemotherapeutics with significant side effects, the search for new drugs remains the gre...

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Bibliografske podrobnosti
izdano v:J Venom Anim Toxins Incl Trop Dis
Main Authors: Barros, Gustavo A. C., Pereira, Andreia V., Barros, Luciana C., Jr, Airton Lourenço, Calvi, Sueli A., Santos, Lucilene D., Barraviera, Benedito, Ferreira, Rui Seabra
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658749/
https://ncbi.nlm.nih.gov/pubmed/26609302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40409-015-0049-0
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