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In vitro activity of phospholipase A(2) and of peptides from Crotalus durissus terrificus venom against amastigote and promastigote forms of Leishmania (L.) infantum chagasi

BACKGROUND: American visceral leishmaniasis is caused by the intracellular parasite Leishmania (L.) infantum chagasi, and transmitted by the sand fly Lutzomyia longipalpis. Since treatment is based on classical chemotherapeutics with significant side effects, the search for new drugs remains the gre...

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Detalhes bibliográficos
Publicado no:J Venom Anim Toxins Incl Trop Dis
Main Authors: Barros, Gustavo A. C., Pereira, Andreia V., Barros, Luciana C., Jr, Airton Lourenço, Calvi, Sueli A., Santos, Lucilene D., Barraviera, Benedito, Ferreira, Rui Seabra
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658749/
https://ncbi.nlm.nih.gov/pubmed/26609302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40409-015-0049-0
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