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Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family
UDP-Glucuronosyltransferases (UGTs) conjugate a glucuronyl group from glucuronic acid to a wide range of lipophilic substrates to form a hydrophilic glucuronide conjugate. The glucuronide generally has decreased bioactivity and increased water solubility to facilitate excretion. Glucuronidation repr...
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| Publicado no: | Drug Metab Dispos |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4658492/ https://ncbi.nlm.nih.gov/pubmed/26354949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.065482 |
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