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Establishment of an artificial β-cell line expressing insulin under the control of doxycycline
AIM: Artificial β-cell lines may offer an abundant source of cells for the treatment of type I diabetes, but insulin secretion in β-cells is tightly regulated in physiological conditions. The Tet-On system is a “gene switch” system, which can induce gene expression by administration of tetracycline...
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| Publicat a: | World J Gastroenterol |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Baishideng Publishing Group Inc
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4658386/ https://ncbi.nlm.nih.gov/pubmed/11925627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v8.i2.367 |
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