Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus

Leptin is abnormally elevated in the plasma of patients with systemic lupus erythematosus (SLE), where it is thought to promote and/or sustain pro-inflammatory responses. Whether this association could reflect an increased genetic susceptibility to develop SLE is not known, and studies of genetic as...

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Publié dans:Clin Immunol
Auteurs principaux: Zhao, Jian, Wu, Hui, Langefeld, Carl D., Kaufman, Kenneth M., Kelly, Jennifer A., Bae, Sang-Cheol, Alarcón-Riquelme, Marta E., Alarcón, Graciela S., Anaya, Juan-Manuel, Criswell, Lindsey A., Freedman, Barry I., Kamen, Diane L., Gilkeson, Gary S., Jacob, Chaim O., James, Judith A., Merrill, Joan T., Gaffney, Patrick M., Sivils, Kathy Moser, Niewold, Timothy B., Petri, Michelle A., Song, Seung Taek, Jeong, Hye-jin, Ramsey-Goldman, Rosalind, Reveille, John D., Scofield, R. Hal, Stevens, Anne M., Boackle, Susan A., Vilá, Luis M., Chang, Deh-Ming, Song, Yeong Wook, Vyse, Timothy J., Harley, John B., Brown, Elizabeth E., Edberg, Jeffrey C., Kimberly, Robert P., Hahn, Bevra H., Grossman, Jennifer M., Tsao, Betty P., La Cava, Antonio
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658308/
https://ncbi.nlm.nih.gov/pubmed/26385092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.09.007
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