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Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling
SHANK-associated RH domain interactor (SHARPIN) inhibits integrins through interaction with the integrin α-subunit. In addition, SHARPIN enhances nuclear factor-kappaB (NF-κB) activity as a component of the linear ubiquitin chain assembly complex (LUBAC). However, it is currently unclear how regulat...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4658161/ https://ncbi.nlm.nih.gov/pubmed/26600301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143423 |
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