Analysis of JC virus DNA replication using a quantitative and high-throughput assay

Progressive Multifocal Leukoencephalopathy (PML) is caused by lytic replication of JC virus (JCV) in specific cells of the central nervous system. Like other polyomaviruses, JCV encodes a large T-antigen helicase needed for replication of the viral DNA. Here, we report the development of a luciferas...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Shin, Jong, Phelan, Paul J., Chhum, Panharith, Bashkenova, Nazym, Yim, Sung, Parker, Robert, Gagnon, David, Gjoerup, Ole, Archambault, Jacques, Bullock, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658058/
https://ncbi.nlm.nih.gov/pubmed/25155200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.07.042
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