Lgr5 Methylation in Cancer Stem Cell Differentiation and Prognosis-Prediction in Colorectal Cancer

OBJECTIVE: Leucine-rich-repeat-containing G-protein-coupled receptor 5 (lgr5) is a candidate marker for colorectal cancer stem cells (CSC). In the current study, we investigated the methylation status within thelgr5 promoter and evaluated its relationship with CSC differentiation, prognosis for colo...

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Pubblicato in:PLoS One
Autori principali: Su, Shasha, Hong, Feng, Liang, Yanling, Zhou, Jieqiong, Liang, Yan, Chen, Kequan, Wang, Xinying, Wang, Zhongqiu, Wang, Zhiqing, Chang, Cassie, Han, Weihua, Gong, Wei, Qin, Haitao, Jiang, Bo, Xiong, Huabao, Peng, Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657969/
https://ncbi.nlm.nih.gov/pubmed/26599100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143513
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