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THE α4β1 INTEGRIN AND THE EDA DOMAIN OF FIBRONECTIN REGULATE A PROFIBROTIC PHENOTYPE IN DERMAL FIBROBLASTS*

Prompt deposition of fibronectin-rich extracellular matrix is a critical feature of normal development and the host-response to injury. Fibronectin isoforms that include the EDA and EDB domains are prominent in these fibronectin matrices. We now report using human dermal fibroblast cultures that the...

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Detalhes bibliográficos
Publicado no:Matrix Biol
Main Authors: Shinde, Arti V., Kelsh, Rhiannon, Peters, John H., Sekiguchi, Kiyotoshi, Van De Water, Livingston, McKeown-Longo, Paula J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657864/
https://ncbi.nlm.nih.gov/pubmed/25433338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2014.11.004
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