Limb Ischemic Perconditioning Attenuates Blood-Brain Barrier Disruption by Inhibiting Activity of MMP-9 and Occludin Degradation after Focal Cerebral Ischemia

Remote ischemic perconditioning (PerC) has been proved to have neuroprotective effects on cerebral ischemia, however, the effect of PerC on the BBB disruption and underlying mechanisms remains largely unknown. To address these issues, total 90 adult male Sprague Dawley (SD) rats were used. The rats...

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Bibliografiske detaljer
Udgivet i:Aging Dis
Main Authors: Ren, Changhong, Li, Ning, Wang, Brian, Yang, Yong, Gao, Jinhuan, Li, Sijie, Ding, Yuchuan, Jin, Kunlin, Ji, Xunming
Format: Artigo
Sprog:Inglês
Udgivet: JKL International LLC 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657812/
https://ncbi.nlm.nih.gov/pubmed/26618042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2015.0812
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