NF-κB activation mediates resistance to IFNβ in MLL-rearranged acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) harboring the t(4;11) translocation is associated with a very poor prognosis; innovative treatment strategies are required to improve the current 5-year survival rate of 30–40%. Interferon β (IFNβ) has shown promise in the treatment of both solid and hematologic ma...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Tracey, L, Streck, CJ, Du, Z, Williams, RF, Pfeffer, LM, Nathwani, AC, Davidoff, AM
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657731/
https://ncbi.nlm.nih.gov/pubmed/20130599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.2
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