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High-throughput screening for modulators of cellular contractile force()

When cellular contractile forces are central to pathophysiology, these forces comprise a logical target of therapy. Nevertheless, existing high-throughput screens are limited to upstream signalling intermediates with poorly defined relationships to such a physiological endpoint. Using cellular force...

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Bibliographic Details
Published in:Integr Biol (Camb)
Main Authors: Park, Chan Young, Zhou, Enhua H., Tambe, Dhananjay, Chen, Bohao, Lavoie, Tera, Dowell, Maria, Simeonov, Anton, Maloney, David J., Marinkovic, Aleksandar, Tschumperlin, Daniel J., Burger, Stephanie, Frykenberg, Matthew, Butler, James P., Stamer, W. Daniel, Johnson, Mark, Solway, Julian, Fredberg, Jeffrey J., Krishnan, Ramaswamy
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657543/
https://ncbi.nlm.nih.gov/pubmed/25953078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ib00054h
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