Antibodies against High Mobility Group Box protein-1 (HMGB1) versus other anti-nuclear antibody fine-specificities and disease activity in systemic lupus erythematosus

INTRODUCTION: The non-histone nuclear protein high mobility group box protein-1 (HMGB1) is typically associated with nucleosomes, but may shuttle between the nucleus and the cytoplasm, and under some conditions also be released extracellularly and participate in systemic inflammation. Monoclonal HMG...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Wirestam, Lina, Schierbeck, Hanna, Skogh, Thomas, Gunnarsson, Iva, Ottosson, Lars, Erlandsson-Harris, Helena, Wetterö, Jonas, Sjöwall, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657231/
https://ncbi.nlm.nih.gov/pubmed/26596890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0856-2
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