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Predicted binding site information improves model ranking in protein docking using experimental and computer-generated target structures

BACKGROUND: Protein-protein interactions (PPIs) mediate the vast majority of biological processes, therefore, significant efforts have been directed to investigate PPIs to fully comprehend cellular functions. Predicting complex structures is critical to reveal molecular mechanisms by which proteins...

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Publicado en:BMC Struct Biol
Main Authors: Maheshwari, Surabhi, Brylinski, Michal
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657198/
https://ncbi.nlm.nih.gov/pubmed/26597230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-015-0050-4
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