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Calculating an optimal box size for ligand docking and virtual screening against experimental and predicted binding pockets

BACKGROUND: Computational approaches have emerged as an instrumental methodology in modern research. For example, virtual screening by molecular docking is routinely used in computer-aided drug discovery. One of the critical parameters for ligand docking is the size of a search space used to identif...

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Detalhes bibliográficos
Publicado no:J Cheminform
Main Authors: Feinstein, Wei P., Brylinski, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468813/
https://ncbi.nlm.nih.gov/pubmed/26082804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-015-0067-5
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