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PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion
P21-activated kinase 4 (PAK4) is a Cdc42 effector protein thought to regulate cell adhesion disassembly in a kinase-dependent manner. We found that PAK4 expression is significantly higher in high-grade human breast cancer patient samples, whereas depletion of PAK4 modifies cell adhesion dynamics of...
Tallennettuna:
| Julkaisussa: | J Cell Biol |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4657161/ https://ncbi.nlm.nih.gov/pubmed/26598620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201501072 |
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