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Effects of caffeine on the human circadian clock in vivo and in vitro
Caffeine’s wakefulness-promoting and sleep-disrupting effects are well established, yet whether caffeine affects human circadian timing is unknown. Here we show that evening caffeine consumption delays the human circadian melatonin rhythm in vivo, and chronic application of caffeine lengthens the ci...
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| Publicado no: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4657156/ https://ncbi.nlm.nih.gov/pubmed/26378246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac5125 |
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