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Effects of caffeine on the human circadian clock in vivo and in vitro

Caffeine’s wakefulness-promoting and sleep-disrupting effects are well established, yet whether caffeine affects human circadian timing is unknown. Here we show that evening caffeine consumption delays the human circadian melatonin rhythm in vivo, and chronic application of caffeine lengthens the ci...

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Vydáno v:Sci Transl Med
Hlavní autoři: Burke, Tina M., Markwald, Rachel R., McHill, Andrew W., Chinoy, Evan D., Snider, Jesse A., Bessman, Sara C., Jung, Christopher M., O’Neill, John S., Wright, Kenneth P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657156/
https://ncbi.nlm.nih.gov/pubmed/26378246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac5125
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