PAN-811 Blocks Chemotherapy Drug-Induced In Vitro Neurotoxicity, While Not Affecting Suppression of Cancer Cell Growth

Chemotherapy often results in cognitive impairment, and no neuroprotective drug is now available. This study aimed to understand underlying neurotoxicological mechanisms of anticancer drugs and to evaluate neuroprotective effects of PAN-811. Primary neurons in different concentrations of antioxidant...

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Bibliographic Details
Published in:Oxid Med Cell Longev
Main Authors: Jiang, Zhi-Gang, Fuller, Steven A., Ghanbari, Hossein A.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657105/
https://ncbi.nlm.nih.gov/pubmed/26640619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9392404
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