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PAN-811 prevents chemotherapy-induced cognitive impairment and preserves neurogenesis in the hippocampus of adult rats

Chemotherapy-induced cognitive impairment (CICI) occurs in a substantial proportion of treated cancer patients, with no drug currently available for its therapy. This study investigated whether PAN-811, a ribonucleotide reductase inhibitor, can reduce cognitive impairment and related suppression of...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Jiang, Zhi-Gang, Winocur, Gordon, Wojtowicz, J. Martin, Shevtsova, Olga, Fuller, Steven, Ghanbari, Hossein A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785016/
https://ncbi.nlm.nih.gov/pubmed/29370277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191866
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