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PGC-1 mediates the regulation of metformin in muscle irisin expression and function

Background: Overweight and obesity are rapidly becoming major global health, social, and economic problems. Irisin is a newly termed hormone that is related to metabolic diseases. In the present study, the mechanism underlying the effect of Metformin on promoting irisin release from skeletal muscle...

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Veröffentlicht in:Am J Transl Res
Hauptverfasser: Yang, Zaigang, Chen, Xu, Chen, Yujuan, Zhao, Qian
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656762/
https://ncbi.nlm.nih.gov/pubmed/26692929
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