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Degradation of retinoid X receptor α by TPA through proteasome pathway in gastric cancer cells

AIM: To investigate and determine the mechanism and signal pathway of tetradecanoylphorbol-1, 3-acetate (TPA) in degradation of RXRα. METHODS: Gastric cancer cell line, BGC-823 was used in the experiments. The expression level of RXRα protein was detected by Western blot. Nuclear and cytoplasmic pro...

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Vydáno v:World J Gastroenterol
Hlavní autoři: Ye, Xiao-Feng, Liu, Su, Wu, Qiao, Lin, Xiao-Feng, Zhang, Bing, Wu, Jia-Fa, Zhang, Ming-Qing, Su, Wen-Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656643/
https://ncbi.nlm.nih.gov/pubmed/12970875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i9.1915
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