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Degradation of retinoid X receptor α by TPA through proteasome pathway in gastric cancer cells
AIM: To investigate and determine the mechanism and signal pathway of tetradecanoylphorbol-1, 3-acetate (TPA) in degradation of RXRα. METHODS: Gastric cancer cell line, BGC-823 was used in the experiments. The expression level of RXRα protein was detected by Western blot. Nuclear and cytoplasmic pro...
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| Publié dans: | World J Gastroenterol |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Baishideng Publishing Group Inc
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4656643/ https://ncbi.nlm.nih.gov/pubmed/12970875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i9.1915 |
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