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Loss of heterozygosity on hromosome 1 in sporadic colorectal carcinoma

AIM: Loss of heterozygosity (LOH) on tumor suppressor genes is believed to play a key role in carcinogenesis of colorectal cancer. When it occurs at a tumor suppressor gene locus with abnormal allele, neoplastic transformation happens. In this study, we analyzed the LOH at 21 loci on chromosome 1 in...

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Detalles Bibliográficos
Publicado en:World J Gastroenterol
Main Authors: Zhou, Chong-Zhi, Qiu, Guo-Qiang, Zhang, Fang, He, Lin, Peng, Zhi-Hai
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656279/
https://ncbi.nlm.nih.gov/pubmed/15133848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i10.1431
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