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Detailed deletion mapping of loss of heterozygosity on 22q13 in sporadic colorectal cancer
AIM: Both development and progression of malignancies occur as a multistep process, requiring the activation of oncogenes and the inactivation of several tumor suppressor genes. The loss of heterozygosity (LOH) of tumor suppressor genes is believed to play a key role in carcinogenesis of colorectal...
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| Veröffentlicht in: | World J Gastroenterol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Baishideng Publishing Group Inc
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4305951/ https://ncbi.nlm.nih.gov/pubmed/15786547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i11.1668 |
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